First period
Toronto Maple Leafs vs New York Islanders prediction today centers on Toronto skating at home as the listed home side against the away Isles in this regular-season matchup.
The early moneyline picture is framed by Toronto’s home-ice setup against New York, with bettors typically valuing last change at Scotiabank Arena in a tight first-period script.
Toronto’s availability profile shapes the opening-20 projections because
Auston Matthews is day to day with a lower-body injury and
Matthew Knies is day to day with a lower-body injury.
Toronto’s first-period defensive outlook is influenced by blue-line absences because
Chris Tanev is out with an upper-body injury and
Brandon Carlo is out with a lower-body injury.
Toronto’s crease expectations also feed into first-period odds because
Anthony Stolarz is out with an upper-body injury while
Joseph Woll and
Dennis Hildeby are available on the roster.
William Nylander stands out as Toronto’s cleanest top-performer angle in this slate because he is listed healthy and positioned to carry a larger share of the scoring load if Matthews is limited.

Second period
Second-period betting leans into matchup depth because Toronto lists multiple healthy forwards in John Tavares, Max Domi, William Nylander, Bobby McMann, Nicholas Robertson, and Calle Jarnkrok.
Toronto’s middle-frame risk management ties back to who is unavailable because
Nicolas Roy is out with an upper-body injury and
Marshall Rifai is out with a wrist injury on long-term injured reserve.
Toronto’s second-period pace projection also depends on which day-to-day skaters dress because Matthews’ lower-body status and Knies’ lower-body status can shift the shot-quality outlook and, by extension, live odds movement.
The Islanders’ ability to keep the game in a grinding second period is baked into the market because New York enters as the away team and Toronto enters as the home team in the listed competitor slate.
Toronto Maple Leafs vs New York Islanders total points line discussion is most sensitive in this period because Toronto’s injury list includes multiple outs on defense and at least one day-to-day star forward.
Third period
Third-period wagering usually tightens around late-game finishing, and Toronto’s finishing profile is supported by healthy top-six options like Nylander and Tavares in the active roster list.
Toronto’s late-game protection metrics in the market are shaded by defensive availability because Tanev remains out and Carlo remains out, which can push bettors toward higher late scoring expectations.
If Matthews is limited or scratched as a day-to-day lower-body case, Toronto’s third-period scoring distribution is projected to tilt even more toward Nylander and the remaining healthy forwards listed on the roster.
The history between these clubs is highlighted by the fact that Toronto and New York are formally listed as competitors in the same regular-season round, with Toronto designated home and New York designated away for this meeting.

Toronto hosts the Islanders on March 17, 2026 at 7:00 PM ET at Scotiabank Arena in Toronto, and where to watch Toronto Maple Leafs vs New York Islanders includes ESPN+ and MSGSN from the broadcast listing; if you’re playing the numbers, track lineup confirmations for Matthews and Knies, shop the best price on Toronto’s side tied to Nylander’s scoring role, and share this article with other Buds fans sizing up the slate.