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First Quarter As the Clemson Tigers prepare to face off against the Louisville Cardinals , the betting lines are buzzing with activity. The Tigers, led by quarterback Cade Klubnik , enter the game as favorites with a moneyline of -230 across major sportsbooks like DraftKings and FanDuel. This indicates a strong confidence in Clemson's ability to start strong and potentially dominate early on. The opening odds for Clemson were slightly less favorable at -218, but have since improved, reflecting growing support from bettors.

<img src="/imgproxy/6CnBlznBY6VpxJ_VV2MmQ1efzALx1TA78RMHr_VCJxg/rs:fit:800:800:false:false/aHR0cHM6Ly9zdG9yYWdlLmdvb2dsZWFwaXMuY29tL3dtdC1nYW1lcy1zZXJ2aWNlLzk3OGE4NDgwMTIzYTA3MDE2YjUyOWNlNGIwZDM2MmZjLmpwZw==?image_id=7be68617-5f4c-421a-a032-093e99d60b15" alt="Dec 3, 2022; Charlotte, NC, USA; Clemson Tigers wide receiver Cole Turner (22) warms up before the ACC Championship game against the North Carolina Tarheels at Bank of America Stadium. Mandatory Credit: Ken Ruinard-USA TODAY NETWORK" title="Dec 3, 2022; Charlotte, NC, USA; Clemson Tigers wide receiver Cole Turner (22) warms up before the ACC Championship game against the North Carolina Tarheels at Bank of America Stadium. Mandatory Credit: Ken Ruinard-USA TODAY NETWORK" /> On the other side of the field, the Cardinals are looking to capitalize on their home advantage at L&N Federal Credit Union Stadium. With a current moneyline of +190, Louisville is seen as the underdog. However, their odds have shifted upwards from an opening line of +158, suggesting some skepticism about their ability to keep pace with Clemson's high-powered offense.

Second Quarter As we move into the second quarter, attention turns to the point spread. Clemson is favored by 6 points according to consensus lines. This spread has seen some fluctuation; it opened at 6.5 points but has since settled slightly lower. This adjustment might be due to recent performances or strategic changes within both teams' lineups.

For those eyeing total points scored in this matchup, sportsbooks like MGM and DraftKings have set an over/under line at 60.5 points. Both teams boast potent offenses capable of lighting up the scoreboard, making this a particularly intriguing aspect for bettors looking for value in high-scoring affairs.

Third Quarter The third quarter often serves as a pivotal moment where momentum can shift dramatically. Bettors will be keenly observing how both teams adjust their strategies post-halftime. For Clemson fans hoping for a decisive victory, maintaining or extending their lead during this period will be crucial.

Louisville's defense will need to step up if they hope to cover the spread or even pull off an upset victory. The Cards' odds trend has been moving upwards recently—an indication that bookmakers and bettors alike are wary of potential vulnerabilities against Clemson's dynamic playmakers.

Fourth Quarter As we approach crunch time in the fourth quarter, all eyes will be on Cade Klubnik and his ability to lead his team under pressure. With consistent performances throughout previous games this season, Klubnik remains a key figure in driving Clemson's success and justifying their favored status in this matchup.

For those considering free picks Clemson Tigers vs Louisville Cardinals or analyzing betting trends further before placing wagers—keep an eye on late-game heroics that could swing outcomes dramatically either way.

Fans can catch all live action when these two powerhouses clash on November 14th at 7:30 PM local time in Louisville (broadcasted nationally via ESPN). Whether you're backing your favorite team or simply enjoying top-tier football competition—this showdown promises excitement from start till finish! Share your thoughts about who'll emerge victorious using #CLEMvsLOU!

Austin Mack

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