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Clemson Tigers - NCAA Football - Odds, Watch, Predictions

Clemson Tigers vs South Carolina Gamecocks: Cade Klubnik Leads the Charge in Rivalry Showdown

November 22, 2025

As the Clemson Tigers prepare to face off against the South Carolina Gamecocks, all eyes are on quarterback Cade Klubnik. The Tigers enter this rivalry game as favorites, with odds at -205 on DraftKings and -196 on FanDuel. The Gamecocks, meanwhile, are underdogs with odds ranging from +160 to +170 across various sportsbooks. The opening moneyline saw a shift in favor of Clemson, indicating strong confidence in their performance.

Clemson Tigers - NCAA Football - Odds, Watch, Predictions

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