Isaiah McGuire

Isaiah McGuire, a professional NFL player, was born on July 27, 2001, in Tulsa, Oklahoma. Standing at 76 inches tall and weighing 268 pounds, McGuire plays as a defensive end (DE) for the Cleveland Browns. He began his football career at Union High School in Tulsa before advancing to the University of Missouri, where he showcased his talents in the Southeastern Conference. Isaiah McGuire's NFL journey commenced when he was drafted by the Cleveland Browns in 2023 during the fourth round as the 126th overall pick. Since joining the Browns, McGuire has played a significant role in the team's defensive lineup. During the 2025 regular season, McGuire played in 17 games, starting in 8 of them. His defensive prowess is highlighted by his accumulation of 2 sacks, 8 tackles for loss (TFL), and 1 forced fumble. Additionally, he achieved 17 tackles, with 13 assists, contributing to a total of 30 combined tackles. McGuire also made 6 quarterback hits, demonstrating his ability to pressure the opposing team's quarterback. His performance reflects a growing defensive skill set, marked by his ability to disrupt offensive plays and contribute significantly to his team's defense. McGuire's contributions underscore his potential as a valuable asset to the Browns' defense.